Institutional Review Board

Franklin University Institutional Review Board (IRB)

The Institutional Review Board (IRB) is an administrative body established to protect the rights and welfare of human research subjects recruited to participate in research activities conducted under the auspices of the institution with which it is affiliated. The Franklin University IRB comprises faculty and staff members, as well as a community member not otherwise affiliated with the University, who are responsible for overseeing research projects involving human subjects.

Franklin University IRB COVID-19 Response

Effective immediately, all face-to-face human subjects research activities must cease until further notice. This includes activities involving Franklin University researchers (faculty, student, staff) at any site. Principal Investigators are expected to pass this notification on to all human subjects research personnel immediately. See the Franklin University IRB’s COVID-19 Response document for more information.

To help research teams through these developing events, the Franklin University IRB has prepared guidelines to assist investigators who can and wish to convert any qualitative, face-to-face data collection plans to virtual means. See the Franklin University IRB’s COVID-19 and Qualitative Research document for more information.

Please contact the IRB Office at with any questions.

Cayuse IRB Login

Franklin University uses Cayuse IRB, a cloud-based software, for protocol management.

First time users click here

Returning users click here

Research & Data Request 

For all Franklin University research and data requests, complete the form below.

Research & data request form

What does the IRB do?

The IRB reviews protocols and has the authority to approve, require modifications in, or disapprove all research activities that fall within its jurisdiction as specified by both the federal regulations and local institutional policy. The IRB makes its independent determination whether to approve or disapprove the protocol based upon whether or not human subjects are adequately protected.

Does my research require IRB review?

The Franklin University IRB reviews and approves any undertaking in which an individual affiliated with the University (faculty, staff, or student) conducts human research.

For purposes of determining which projects require IRB review, Franklin University adheres to the definitions of ‘research’ and ‘human subject’ presented in the Department of Health and Human Services (DHHS) Code of Federal Regulations (45 CFR part 46). 

Research means a systematic investigation, including research development, testing, and evaluation, designed to develop or contribute to generalizable knowledge [45 CFR 46.102(l)]. 

Human subject means a living individual about whom an investigator (whether professional or student) conducts research and (i) Obtains information or biospecimens through intervention or interaction with the individual, and uses, studies, or analyzes the information or biospecimens; or (ii) Obtains, uses, studies, analyzes, or generates identifiable private information or identifiable biospecimens. [45 CFR 46.102(e)(1)].

Where can I find more information about the regulations and human subjects research?

The Department of Health and Human Services (HHS) regulations at 45 CFR part 46 stipulate substantive and procedural requirements for investigators and institutions engaged in research. You can read the Code of Federal Regulations regarding the Protection of Human Subjects here.

Check out the Office for Human Research Protections (OHRP) to learn more about protecting the rights, welfare, and wellbeing of human subjects involved in research.

Cayuse Account Access

Returning Users 

Returning users may access the regular Cayuse IRB login here.

New Users

Follow these four steps to set up your Cayuse IRB account. If you need additional assistance, click here for a step-by-step guide for first-time users.

  1. Click here to create a password. 
  2. Provide your Franklin University username and click Request Password. You will receive an email with a link to create a new password. 
  3. Once you set a new password, use the regular Cayuse IRB login.* 
  4. Once you are in the Cayuse Research Suite, click on ‘Cayuse IRB (Human Studies Compliance)'. This will take you to your Dashboard.

* Make sure you log out of the registration link and use the regular login to access your Cayuse IRB Dashboard


Did you get an error stating, “We don’t recognize that username”?*
*If you are a doctoral student, you will be added to Cayuse IRB once you are enrolled in GRAD 903.

To request access to Cayuse IRB, please complete the Cayuse Access Request Form. Please note: it may take up to 48 hours to complete your request. 

Additional Information